Set in the United States, Dog Gone Flea-bitten Mutt is the story of Jimmy Brand, an old Mafia boss who has been betrayed, and a price put on his head by both the police and his former companions in crime. Hiding out in his old friend Joe's scrapyard, he looks back on his life and hatches a harebrained plot to escape. In parallel to this, a series of crazy serial car chases take place, involving increasingly bizarre characters and stories that branch out into infinity, which give an idea of the author's unbounded love of noir literature and cinema, plus vintage cars.